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Directed vaccination against pneumococcal disease

Immunization strategies against commensal bacterial pathogens have long focused on eradicating asymptomatic carriage as well as disease, resulting in changes in the colonizing microflora with unknown future consequences. Additionally, current vaccines are not easily adaptable to sequence... Full description

1st Person: Li, Yi
Additional Persons: Hill, Andrew; Beitelshees, Marie; Shao, Shuai; Lovell, Jonathan F.; Davidson, Bruce A.; Knight, Paul R.; Hakansson, Anders P.; Pfeifer, Blaine A.; Jones, Charles H.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 113, No. 25 (2016), p. 6898-6903
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Type of Publication: Article
Language: English
Published: 2016
Keywords: virulence
S. pneumoniae
pneumococcal
biofilm
vaccine
Online: Volltext
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