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Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis

The exocyst complex regulates the last steps of exocytosis, which is essential to organisms across kingdoms. In humans, its dysfunction is correlated with several significant diseases, such as diabetes and cancer progression. Investigation of the dynamic regulation of the evolutionarily conserved... Full description

1st Person: Zhang, Chunhua verfasserin
Additional Persons: Brown, Michelle Q. verfasserin; van de Ven, Wilhelmina verfasserin; Zhang, Zhi-Min verfasserin; Wu, Bin verfasserin; Young, Michael C. verfasserin; Synek, Lukáš verfasserin; Borchardt, Dan verfasserin; Harrison, Reed verfasserin; Pan, Songqin verfasserin; Luo, Nan verfasserin; Huang, Yu-ming M. verfasserin; Ghang, Yoo-Jin verfasserin; Ung, Nolan verfasserin; Li, Ruixi verfasserin; Isley, Jonathan verfasserin; Morikis, Dimitrios verfasserin; Song, Jikui verfasserin; Guo, Wei verfasserin; Hooley, Richard J. verfasserin; Chang, Chia-en A. verfasserin; Yang, Zhenbiao verfasserin; Zarsky, Viktor verfasserin; Muday, Gloria K. verfasserin; Hicks, Glenn R. verfasserin; Raikhel, Natasha V. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 113, No. 1 (2016), p. E41-E50
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Type of Publication: Article
Language: English
Published: 2016
Keywords: endosidin2
exocytosis
exocyst
EXO70
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