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Inference of transcriptional regulation in cancers

Despite the rapid accumulation of tumor-profiling data and transcription factor (TF) ChIP-seq profiles, efforts integrating TF binding with the tumor-profiling data to understand how TFs regulate tumor gene expression are still limited. To systematically search for cancer-associated TFs, we... Full description

1st Person: Jiang, Peng
Additional Persons: Freedman, Matthew L.; Liu, Jun S.; Liu, Xiaole Shirley
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 112, No. 25 (2015), p. 7731-7736
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Type of Publication: Article
Language: English
Published: 2015
Keywords: regulatory inference
tumor profiling
transcription factor
RNA-binding protein
Online: Volltext
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