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Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl⁻ channel TMEM16A

The developmental rehearsal for the debut of hearing is marked by massive changes in the membrane properties of hair cells (HCs) and spiral ganglion neurons (SGNs). Whereas the underlying mechanisms for the developing HC transition to mature stage are understood in detail, the maturation of SGNs... Full description

1st Person: Zhang, Xiao-Dong
Additional Persons: Lee, Jeong-Han; Lv, Ping; Chen, Wei Chun; Kim, Hyo Jeong; Wei, Dongguang; Wang, Wenying; Sihn, Choong-Ryoul; Jo Doyle, Karen; Rock, Jason R.; Chiamvimonvat, Nipavan; Yamoah, Ebenezer N.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 112, No. 8 (2015), p. 2575-2580
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Type of Publication: Article
Language: English
Published: 2015
Keywords: hearing
spiral ganglion neurons
action potentials
calcium-activated chloride channels
Online: Volltext
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