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Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program

Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation and... Full description

1st Person: Zhang, Feng verfasserin
Additional Persons: Tanasa, Bogdan verfasserin; Merkurjev, Daria verfasserin; Lin, Chijen verfasserin; Song, Xiaoyuan verfasserin; Li, Wenbo verfasserin; Tan, Yuliang verfasserin; Liu, Zhijie verfasserin; Zhang, Jie verfasserin; Ohgi, Kenneth A. verfasserin; Krones, Anna verfasserin; Skowronska-Krawczyk, Dorota verfasserin; Rosenfeld, Michael G. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 112, No. 5 (2015), p. 1380-1385
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Type of Publication: Article
Language: English
Published: 2015
Keywords: LDB1
ASCL1
MTA2
looping
enhancer
Online: Volltext
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