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A Family of IFN-λ-Inducible 65-kD GTPases Protects Against Bacterial Infection

Immune interferon gamma (IFN-γ) is essential for mammalian host defense against intracellular pathogens. IFN-γ induces nearly 2000 host genes, yet few have any assigned function. Here, we examined a complete mouse 65-kilodalton (kD) guanylate-binding protein (Gbp) gene family as part of a... Full description

1st Person: Kim, Bae-Hoon
Additional Persons: Shenoy, Avinash R. verfasserin; Kumar, Pradeep verfasserin; Das, Rituparna verfasserin; Tiwari, Sangeeta verfasserin; MacMicking, John D. verfasserin
Source: in Science Vol. 332, No. 6030 (2011), p. 717-721
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Type of Publication: Article
Language: English
Published: 2011
Keywords: research-article
Online: Volltext
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