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Icaritin ameliorates carbon tetrachloride-induced acute liver injury mainly because of the antioxidative function through estrogen-like effects

To investigate the effects of icaritin, an active ingredient extracted from Epimedium Sagittatum (Sieb. et Zucc.), on CCl4-induced liver injury and its possible mechanisms. Hepatocytes isolated from Sprague-Dawley male rats were treated with 3 mmol/L CCl4 for 24 h to induce acute liver cell... Full description

1st Person: Liu, Peng
Additional Persons: Jin, Xiang verfasserin; Lv, Hao verfasserin; Li, Jing verfasserin; Xu, Wen verfasserin; Qian, Hai-hua verfasserin; Yin, Zhengfeng verfasserin
Source: in In vitro cellular & developmental biology Vol. 50, No. 10 (2014), p. 899-908
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Type of Publication: Article
Language: English
Published: 2014
Keywords: research-article
Online: Volltext
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