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Diet-Induced Obesity Dramatically Reduces the Efficacy of a 2009 Pandemic H1N1 Vaccine in a Mouse Model

Background. Obesity, a risk factor for increased severity of diverse diseases, is believed to have negative impact on vaccine efficacy. Recently, mortality has emerged as an outcome of pandemic influenza A virus subtype H1N1, necessitating development of effective vaccine strategies. Here we... Full description

1st Person: Kim, Yong-Hoon verfasserin
Additional Persons: Kim, Jeong-Ki verfasserin; Kim, Doo-Jin verfasserin; Nam, Jeong-Hyun verfasserin; Shim, Sang-Moo verfasserin; Choi, Young-Ki verfasserin; Lee, Chul-Ho verfasserin; Poo, Haryoung verfasserin
Source: in The Journal of Infectious Diseases Vol. 205, No. 2 (2012), p. 244-251
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Type of Publication: Article
Language: English
Published: 2012
Keywords: research-article
Online: Volltext
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