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LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection

Recognition of viral nucleic acids by pattern recognition receptors initiates type I IFN induction and innate antiviral immune response. Here we show that LSm14A, a member of the LSm family involved in RNA processing in the processing bodies, binds to synthetic or viral RNA and DNA and mediates... Full description

1st Person: Li, Ying
Additional Persons: Chen, Rui verfasserin; Zhou, Qian verfasserin; Xu, Zhisheng verfasserin; Li, Chao verfasserin; Wang, Shuai verfasserin; Mao, Aiping verfasserin; Zhang, Xiaodong verfasserin; He, Weiwu verfasserin; Shu, Hong-Bing verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 109, No. 29 (2012), p. 11770-11775
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Type of Publication: Article
Language: English
Published: 2012
Keywords: research-article
Online: Volltext
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