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Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with progressive memory loss, severe dementia, and hallmark neuropathological markers, such as deposition of amyloid-β (Aβ) peptides in senile plaques and accumulation of hyperphosphorylated tau proteins in... Full description

1st Person: Ardiles, Álvaro O.
Additional Persons: Tapia-Rojas, Cheril C. verfasserin; Mandal, Madhuchhanda verfasserin; Alexandre, Frédéric verfasserin; Kirkwood, Alfredo verfasserin; Inestrosa, Nibaldo C. verfasserin; Palacios, Adrian G. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 109, No. 34 (2012), p. 13835-13840
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Type of Publication: Article
Language: English
Published: 2012
Keywords: research-article
Online: Volltext
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