Katalog GES

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

CD47, a "don't eat me" signal for phagocytic cells, is expressed on the surface of all human solid tumor cells. Analysis of patient tumor and matched adjacent normal (nontumor) tissue revealed that CD47 is overexpressed on cancer cells. CD47 mRNA expression levels correlated with a decreased... Full description

1st Person: Willingham, Stephen B.
Additional Persons: Volkmer, Jens-Peter verfasserin; Gentles, Andrew J. verfasserin; Sahoo, Debashis verfasserin; Dalerba, Piero verfasserin; Mitra, Siddhartha S. verfasserin; Wang, Jian verfasserin; Contreras-Trujillo, Humberto verfasserin; Martin, Robin verfasserin; Cohen, Justin D. verfasserin; Lovelace, Patricia verfasserin; Scheeren, Ferenc A. verfasserin; Chao, Mark P. verfasserin; Weiskopf, Kipp verfasserin; Tang, Chad verfasserin; Volkmer, Anne Kathrin verfasserin; Naik, Tejaswitha J. verfasserin; Storm, Theresa A. verfasserin; Mosley, Adriane R. verfasserin; Edris, Badreddin verfasserin; Schmid, Seraina M. verfasserin; Sun, Chris K. verfasserin; Chua, Mei-Sze verfasserin; Murillo, Oihana verfasserin; Rajendran, Pradeep verfasserin; Cha, Adriel C. verfasserin; Chin, Robert K. verfasserin; Kim, Dongkyoon verfasserin; Adorno, Maddalena verfasserin; Raveh, Tal verfasserin; Tseng, Diane verfasserin; Jaiswal, Siddhartha verfasserin; Enger, Per Øyvind verfasserin; Steinberg, Gary K. verfasserin; Li, Gordon verfasserin; So, Samuel K. verfasserin; Majeti, Ravindra verfasserin; Harsh, Griffith R. verfasserin; van de Rijn, Matt verfasserin; Teng, Nelson N. H. verfasserin; Sunwoo, John B. verfasserin; Alizadeh, Ash A. verfasserin; Clarke, Michael F. verfasserin; Weissman, Irving L. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 109, No. 17 (2012), p. 6662-6667
More Articles
Type of Publication: Article
Language: English
Published: 2012
Keywords: research-article
Online: Volltext
  Search for full text



Similar Items

Cannot find similar records

Library Services

Search Options

Quick links