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Regulation of neuroblastoma differentiation by forkhead transcription factors FOXO1/3/4 through the receptor tyrosine kinase PDGFRA

Neuroblastoma is a common childhood malignant tumor originated from the neural crest-derived sympathetic nervous system. A crucial early event in neuroblastoma pathogenesis is arrested differentiation of neuroblasts at various stages. Treatment of neuroblastoma with TPA and PDGF-BB leads to... Full description

1st Person: Mei, Yang
Additional Persons: Wang, Zhanxiang verfasserin; Zhang, Lei verfasserin; Zhang, Yiru verfasserin; Li, Xiaoyu verfasserin; Liu, Huihui verfasserin; Ye, Jing verfasserin; You, Han verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 109, No. 13 (2012), p. 4898-4903
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Type of Publication: Article
Language: English
Published: 2012
Keywords: research-article
Online: Volltext
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