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FG-Rich Repeats of Nuclear Pore Proteins Form a Three-Dimensional Meshwork with Hydrogel-like Properties

Nuclear pore complexes permit rapid passage of cargoes bound to nuclear transport receptors, but otherwise suppress nucleocytoplasmic fluxes of inert macromolecules ≥30 kilodaltons. To explain this selectivity, a sieve structure of the permeability barrier has been proposed that is created... Full description

1st Person: Frey, Steffen
Additional Persons: Richter, Ralf P. verfasserin; Görlich, Dirk verfasserin
Source: in Science Vol. 314, No. 5800 (2006), p. 815-817
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Type of Publication: Article
Language: English
Published: 2006
Keywords: research-article
Online: Volltext
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