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Structural Insights into Group II Intron Catalysis and Branch-Site Selection

Group II self-splicing introns catalyze autoexcision from precursor RNA transcripts by a mechanism strikingly similar to that of the spliceosome, an RNA-protein assembly responsible for splicing together the protein-coding parts of most eukaryotic pre-mRNAs. Splicing in both cases initiates via... Full description

1st Person: Zhang, Lan
Additional Persons: Doudna, Jennifer A. verfasserin
Source: in Science Vol. 295, No. 5562 (2002), p. 2084-2088
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Type of Publication: Article
Language: English
Published: 2002
Keywords: research-article
Online: Volltext
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