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Regulation of Muscle Acetylcholine Sensitivity by Muscle Activity in Cell Culture

Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less $^{125}$I-labeled α-bungarotoxin... Full description

1st Person: Cohen, Stephen A.
Additional Persons: Fischbach, Gerald D. verfasserin
Source: in Science Vol. 181, No. 4094 (1973), p. 76-78
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Type of Publication: Article
Language: English
Published: 1973
Keywords: research-article
Online: Volltext
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500 |a Copyright: Copyright 1973 American Association for the Advancement of Science 
520 |a Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less $^{125}$I-labeled α-bungarotoxin than inactive fibers. 
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700 1 |a Fischbach, Gerald D.  |e verfasserin  |4 aut 
773 0 8 |i in  |t Science  |g Vol. 181, No. 4094 (1973), p. 76-78  |q 181:4094<76-78  |w (DE-601)JST078179041  |x 1095-9203 
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952 |d 181  |j 1973  |e 4094  |h 76-78 

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