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Regulation of Muscle Acetylcholine Sensitivity by Muscle Activity in Cell Culture

Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less $^{125}$I-labeled α-bungarotoxin... Full description

1st Person: Cohen, Stephen A.
Additional Persons: Fischbach, Gerald D. verfasserin
Source: in Science Vol. 181, No. 4094 (1973), p. 76-78
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Type of Publication: Article
Language: English
Published: 1973
Keywords: research-article
Online: Volltext
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Summary: Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less $^{125}$I-labeled α-bungarotoxin than inactive fibers.
Item Description: Copyright: Copyright 1973 American Association for the Advancement of Science
Physical Description: Online-Ressource
ISSN: 1095-9203

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