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Overexpression of Transforming Growth Factor α in Psoriatic Epidermis

Transforming growth factor α (TGF-α) is produced by and required for the growth of epithelial cells and is angiogenic in vivo. Since epidermal hyperplasia and angiogenesis are hallmarks of psoriasis TGF-α gene expression was analyzed in epidermal biopsies of normal and psoriatic skin. TGF-α... Full description

1st Person: Elder, James T.
Additional Persons: Fisher, Gary J.; Lindquist, Patricia B.; Bennett, Gregory L.; Pittelkow, Mark R.; Coffey, Robert J.; Ellingsworth, Larry; Derynck, Rik; Voorhees, John J.
Source: in Science Vol. 243, No. 4892 (1989), p. 811-814
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Type of Publication: Article
Language: English
Published: 1989
Online: Volltext
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