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Cytochrome c Release and Apoptosis Induced by Mitochondrial Targeting of Nuclear Orphan Receptor TR3

TR3, an immediate-early response gene and an orphan member of the steroid-thyroid hormone-retinoid receptor superfamily of transcription factors, regulates apoptosis through an unknown mechanism. In response to apoptotic stimuli, TR3 translocates from the nucleus to mitochondria to induce... Full description

1st Person: Li, Hui
Additional Persons: Kolluri, Siva Kumar verfasserin; Gu, Jian verfasserin; Dawson, Marcia I. verfasserin; Cao, Xihua verfasserin; Hobbs, Peter D. verfasserin; Lin, Bingzhen verfasserin; Chen, Guo-quen verfasserin; Lu, Jiang-song verfasserin; Lin, Feng verfasserin; Xie, Zhihua verfasserin; Fontana, Joseph A. verfasserin; Reed, John C. verfasserin; Zhang, Xiao-kun verfasserin
Source: in Science Vol. 289, No. 5482 (2000), p. 1159-1164
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Type of Publication: Article
Language: English
Published: 2000
Keywords: research-article
Online: Volltext
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