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Mutant <italic>Ikzf1, Kras</italic> G12D , and <italic>Notch1</italic> cooperate in T lineage leukemogenesis and modulate responses to targeted agents

Mice that accurately model the genetic diversity found in human cancer are valuable tools for interrogating disease mechanisms and investigating novel therapeutic strategies. We performed insertional mutagenesis with the MOL4070LTR retrovirus in Mx1-Cre, Kras G12D mice and generated a... Full description

1st Person: Dail, Monique
Additional Persons: Li, Qing verfasserin; McDaniel, Andrew verfasserin; Wong, Jason verfasserin; Akagi, Keiko verfasserin; Huang, Ben verfasserin; Kang, Hio Chung verfasserin; Kogan, Scott C. verfasserin; Shokat, Kevan verfasserin; Wolff, Linda verfasserin; Braun, Benjamin S. verfasserin; Shannon, Kevin verfasserin; Copeland, Neal G. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 107, No. 11 (2010), p. 5106-5111
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Type of Publication: Article
Language: English
Published: 2010
Keywords: research-article
Online: Volltext
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