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Involvement of Brain Opiate Receptors in the Immune-Suppressive Effect of Morphine

We previously reported that a single systemic injection of a high dose of morphine (≥ 20 mg/kg) transiently suppresses splenic natural killer cell cytotoxicity in rats. The present study examined the possibility that the immune-suppressive effect of morphine is mediated by opiate receptors in... Full description

1st Person: Shavit, Yehuda
Additional Persons: Depaulis, Antoine; Martin, Fredricka C.; Terman, Gregory W.; Pechnick, Robert N.; Zane, Cynthia J.; Gale, Robert Peter; Liebeskind, John C.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 83, No. 18 (1986), p. 7114-7117
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Type of Publication: Article
Language: English
Published: 1986
Keywords: Neurobiology
Intracerebroventricular Injection
Naltrexone
Natural Killer Cells
N-methyl Morphine
Online: Volltext
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