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A Unique Mechanism Regulating Gene Expression: Translational Inhibition by a Complementary RNA Transcript (micRNA)

The expression of the genes for the major outer membrane proteins OmpF and OmpC are osmoregulated. The ompC locus was found to be transcribed bidirectionally under conditions of high osmolarity and a 174-base transcript encoded upstream of ompC was found to inhibit the OmpF production and to... Full description

1st Person: Mizuno, Takeshi
Additional Persons: Chou, Mei-Yin verfasserin; Inouye, Masayori verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 81, No. 7 (1984), p. 1966-1970
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Type of Publication: Article
Language: English
Published: 1984
Keywords: research-article
Biochemistry
Shine-Dalgarno Sequence
Initiation Codon
Outer Membrane Proteins
Osmoregulation
Online: Volltext
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