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Inheritance of Human Breast Cancer: Evidence for Autosomal Dominant Transmission in High-Risk Families

Segregation analysis of breast cancer in families can provide the logical basis and the specific genetic models for mapping and identifying genes responsible for human breast cancer. Patterns of breast cancer occurrence in families were investigated by complex segregation analysis. In a sample of... Full description

1st Person: Newman, Beth
Additional Persons: Austin, Melissa A. verfasserin; Lee, Ming verfasserin; King, Mary-Claire verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 85, No. 9 (1988), p. 3044-3048
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Type of Publication: Article
Language: English
Published: 1988
Keywords: research-article
Breast Neoplasms
Gene Mapping
Medical Genetics
Pedigree Analysis
Online: Volltext
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