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Nitric Oxide Stimulates Auto-ADP-Ribosylation of Glyceraldehyde-3-Phosphate Dehydrogenase

Nitric oxide generation in brain cytosolic fractions markedly enhances ADP-ribosylation of a single 37-kDa protein. By utilizing a biotinylated NAD and avidin affinity chromatography, we purified this protein. Partial amino acid sequencing establishes its identity as glyceraldehyde-3-phosphate... Full description

1st Person: Zhang, Jie
Additional Persons: Snyder, Solomon H.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 89, No. 20 (1992), p. 9382-9385
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Type of Publication: Article
Language: English
Published: 1992
Keywords: Biochemistry
Glutamate Neurotoxicity
Biotinylated NAD
Online: Volltext
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