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Water-Soluble Porphyrins as a Dual-Function Molecular Imaging Platform for MRI and Fluorescence Zinc Sensing

We report a molecular platform for dual-function fluorescence/MRI sensing of mobile zinc. Zinc-selective binding units were strategically attached to a water-soluble porphyrin template. The synthetic strategy for achieving the designed target ligand is flexible and convenient, and the key... Full description

1st Person: Zhang, Xiao-an
Additional Persons: Lovejoy, Katherine S.; Jasanoff, Alan; Lippard, Stephen J.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 104, No. 26 (2007), p. 10780-10785
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Type of Publication: Article
Language: English
Published: 2007
Keywords: Multifunctional imaging
MRI contrast agent
Fluorescence dye
Cell permeability
Online: Volltext
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