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Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

Inhibitors of the serotonin transporter (SERT) and norepinephrine transporter (NET) are widely used in the treatment of major depressive disorder. Although SERT/NET selectivity is a key determinant for the therapeutic properties of these drugs, the molecular determinants defining SERT/NET... Full description

1st Person: Andersen, Jacob
Additional Persons: Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna M. R.; Eildal, Jonas N. N.; Bond, Andrew D.; Bøgesø, Klaus P.; Bang-Andersen, Benny; Kristensen, Anders S.; Strømgaard, Kristian
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 108, No. 29 (2011), p. 12137-12142
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Type of Publication: Article
Language: English
Published: 2011
Online: Volltext
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