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Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis

PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. We recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. To... Full description

1st Person: Xiao, Junyu
Additional Persons: Engel, James L. verfasserin; Zhang, Ji verfasserin; Chen, Mark J. verfasserin; Manning, Gerard verfasserin; Dixon, Jack E. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 108, No. 29 (2011), p. 11860-11865
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Type of Publication: Article
Language: English
Published: 2011
Keywords: research-article
Online: Volltext
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