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Combination of Interleukins 3 and 6 Preserves Stem Cell Function in Culture and Enhances Retrovirus-Mediated Gene Transfer into Hematopoietic Stem Cells

The effects of several hematopoietic growth factors on primitive murine bone marrow progenitor cells [colony-forming unit(s)-spleen (CFU-S)] have been investigated during culture for 2-6 days. Interleukin 3 (IL-3) was required for CFU-S survival in culture, and the combination of IL-3 and... Full description

1st Person: Bodine, David M.
Additional Persons: Karlsson, Stefan verfasserin; Nienhuis, Arthur W. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 86, No. 22 (1989), p. 8897-8901
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Type of Publication: Article
Language: English
Published: 1989
Keywords: research-article
Genetics
Growth Factors
Online: Volltext
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