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Relative Stability of α - and β -Globin Messenger RNAs in Homozygous β+Thalassemia

The relative concentrations of α -, β -, and γ -globin mRNA sequences were measured in bone marrow nuclear and cytoplasmic RNA and in RNA from peripheral blood reticulocytes of three patients with homozygous β+thalassemia. Our results suggest that the quantitative deficiency in β -globin... Full description

1st Person: Nienhuis, Arthur W.
Additional Persons: Turner, Patricia verfasserin; Benz, Edward J. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 74, No. 9 (1977), p. 3960-3964
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Type of Publication: Article
Language: English
Published: 1977
Keywords: research-article
Genetics
Nuclear RNA
Complementary DNA
γ mRNA
Erythroid cells
Online: Volltext
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