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Horseshoe Crab Acetyl Group-Recognizing Lectins Involved in Innate Immunity are Structurally Related to Fibrinogen

We have characterized and cloned newly isolated lectins from hemolymph plasma of the horseshoe crab Tachypleus tridentatus, which we named tachylectins 5A and 5B (TLs-5). TLs-5 agglutinated all types of human erythrocytes and Gram-positive and Gram-negative bacteria. TLs-5 specifically recognize... Full description

1st Person: Gokudan, Soutaro
Additional Persons: Muta, Tatsushi verfasserin; Tsuda, Ryoko verfasserin; Koori, Kumiko verfasserin; Kawahara, Takeshi verfasserin; Seki, Noriaki verfasserin; Mizunoe, Yoshimitsu verfasserin; Wai, Sun N. verfasserin; Iwanaga, Sadaaki verfasserin; Kawabata, Shun-ichiro verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 96, No. 18 (1999), p. 10086-10091
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Type of Publication: Article
Language: English
Published: 1999
Keywords: research-article
Biochemistry
Online: Volltext
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