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Role of Mitochondrial Lactate Dehydrogenase and Lactate Oxidation in the Intracellular Lactate Shuttle

To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo, isolated rat liver, cardiac, and skeletal muscle mitochondria were incubated with lactate, pyruvate, glutamate, and succinate. As well, α -cyano-4-hydroxycinamate... Full description

1st Person: Brooks, George A.
Additional Persons: Dubouchaud, Herve; Brown, Marcia; Sicurello, James P.; Butz, C. Eric
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 96, No. 3 (1999), p. 1129-1134
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Type of Publication: Article
Language: English
Published: 1999
Keywords: Physiology
Online: Volltext
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