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An Inhibitor of the Microsomal Triglyceride Transfer Protein Inhibits apoB Secretion from HepG2 Cells

The microsomal triglyceride (TG) transfer protein is a heterodimeric lipid transfer protein that catalyzes the transport of triglyceride, cholesteryl ester, and phosphatidylcholine between membranes. Previous studies showing that the proximal cause of abetalipoproteinemia is an absence of MTP... Full description

1st Person: Jamil, Haris
Additional Persons: Gordon, David A. verfasserin; Eustice, David C. verfasserin; Brooks, Cindy M. verfasserin; Dickson, John K. verfasserin; Chen, Ying verfasserin; Ricci, Beverly verfasserin; Chu, Ching-Hsuen verfasserin; Harrity, Thomas W. verfasserin; Ciosek, Carl P. verfasserin; Biller, Scott A. verfasserin; Gregg, Richard E. verfasserin; Wetterau, John R. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 93, No. 21 (1996), p. 11991-11995
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Type of Publication: Article
Language: English
Published: 1996
Keywords: research-article
Pharmacology
Lipoproteins
Lipid transfer protein
Protein disulfide isomerase
Atherosclerosis
Online: Volltext
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