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The Substrate Specificity-Determining Amino Acid Code of 4-Coumarate:CoA Ligase

To reveal the structural principles determining substrate specificity of 4-coumarate:CoA ligase (4CL), the crystal structure of the phenylalanine activation domain of gramicidin S synthetase was used as a template for homology modeling. According to our model, 12 amino acid residues lining the... Full description

1st Person: Schneider, Katja
Additional Persons: Hövel, Klaus verfasserin; Witzel, Kilian verfasserin; Hamberger, Björn verfasserin; Schomburg, Dietmar verfasserin; Kombrink, Erich verfasserin; Stuible, Hans-Peter verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 100, No. 14 (2003), p. 8601-8606
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Type of Publication: Article
Language: English
Published: 2003
Keywords: research-article
Plant Biology
Online: Volltext
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