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Metastasis-Associated Protein 1 (MTA1) Is an Essential Downstream Effector of the c-MYC Oncoprotein

The c-myc oncogene is among the most commonly overexpressed genes in human cancer. c-myc encodes a basic helix-loop-helix/leucine zipper (bHLH/LZ) transcription factor (c-MYC) that activates a cascade of downstream targets that ultimately mediate cellular transformation. Although a large number... Full description

1st Person: Zhang, Xiao-yong
Additional Persons: DeSalle, Lauren M.; Patel, Jagruti H.; Capobianco, Anthony J.; Yu, Duonan; Thomas-Tikhonenko, Andrei; McMahon, Steven B.; Vogt, Peter K.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 102, No. 39 (2005), p. 13968-13973
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Type of Publication: Article
Language: English
Published: 2005
Keywords: Nucleosome remodeling and deacetylating
Epithelial-to-mesenchymal transition
Online: Volltext
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