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Epithelial NF-κB Activation Promotes Urethane-Induced Lung Carcinogenesis

Chronic inflammation is linked to carcinogenesis in several organ systems. In the lungs, NF-κB, a central effector of inflammatory responses, is frequently activated in non-small-cell lung cancer, but its role in tumor promotion has not been studied. Several lines of evidence indicate that ethyl... Full description

1st Person: Stathopoulos, Georgios T.
Additional Persons: Sherrill, Taylor P.; Cheng, Dong-Sheng; Scoggins, Robert M.; Han, Wei; Polosukhin, Vasiliy V.; Connelly, Linda; Yull, Fiona E.; Fingleton, Barbara; Blackwell, Timothy S.
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 104, No. 47 (2007), p. 18514-18519
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Type of Publication: Article
Language: English
Published: 2007
Keywords: Apoptosis
Cancer
Inflammation
Airway
Adenocarcinoma
Online: Volltext
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