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Differences in the RNA Binding Sites of Iron Regulatory Proteins and Potential Target Diversity

Posttranscriptional regulation of genes of mammalian iron metabolism is mediated by the interaction of iron regulatory proteins (IRPs) with RNA stem-loop sequence elements known as iron-responsive elements (IREs). There are two identified IRPs, IRP1 and IRP2, each of which binds consensus IREs... Full description

1st Person: Butt, Julea
Additional Persons: Kim, Hae-Yeong verfasserin; Basilion, James P. verfasserin; Cohen, Seth verfasserin; Iwai, Kazuhiro verfasserin; Philpott, Caroline C. verfasserin; Altschul, Stephen verfasserin; Klausner, Richard D. verfasserin; Rouault, Tracey A. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 93, No. 9 (1996), p. 4345-4349
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Type of Publication: Article
Language: English
Published: 1996
Keywords: research-article
Cell Biology
Online: Volltext
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