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In vitro Isolation and Identification of Human Immunodeficiency Virus (HIV) Variants with Reduced Sensitivity to C-2 Symmetrical Inhibitors of HIV Type 1 Protease

Protease inhibitors are another class of compounds for treatment of human immunodeficiency virus (HIV)-caused disease. The emergence of resistance to the current anti-HIV drugs makes the determination of potential resistance to protease inhibitors imperative. Here we describe the isolation of an... Full description

1st Person: Otto, M. J.
Additional Persons: Garber, S. verfasserin; Winslow, D. L. verfasserin; Reid, C. D. verfasserin; Aldrich, P. verfasserin; Jadhav, P. K. verfasserin; Patterson, C. E. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 90, No. 16 (1993), p. 7543-7547
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Type of Publication: Article
Language: English
Published: 1993
Keywords: research-article
Biochemistry
AIDS
Resistance
Online: Volltext
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