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Cessation of Rapid Late Endosomal Tubulovesicular Trafficking in Niemann-Pick Type C1 Disease

Niemann-Pick type C1 (NPC1) disease results from a defect in the NPC1 protein and is characterized by a pathological accumulation of cholesterol and glycolipids in endocytic organelles. We followed the biosynthesis and trafficking of NPC1 with the use of a functional green fluorescent... Full description

1st Person: Zhang, Mei
Additional Persons: Dwyer, Nancy K. verfasserin; Love, Dona C. verfasserin; Cooney, Adele verfasserin; Comly, Marcy verfasserin; Neufeld, Edward verfasserin; Pentchev, Peter G. verfasserin; Blanchette-Mackie, E. Joan verfasserin; Hanover, John A. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 98, No. 8 (2001), p. 4466-4471
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Type of Publication: Article
Language: English
Published: 2001
Keywords: research-article
Cell Biology
Online: Volltext
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