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Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients

Molecules differentially expressed in blood vessels among organs or between damaged and normal tissues, are attractive therapy targets; however, their identification within the human vasculature is challenging. Here we screened a peptide library in cancer patients to uncover ligand-receptors... Full description

1st Person: Staquicini, Fernanda I.
Additional Persons: Cardó-Vila, Marina verfasserin; Kolonin, Mikhail G. verfasserin; Trepel, Martin verfasserin; Edwards, Julianna K. verfasserin; Nunes, Diana N. verfasserin; Sergeeva, Anna verfasserin; Efstathiou, Eleni verfasserin; Sun, Jessica verfasserin; Almeida, Nalvo F. verfasserin; Tu, Shi-Ming verfasserin; Botz, Gregory H. verfasserin; Wallace, Michael J. verfasserin; O'Connell, David J. verfasserin; Krajewski, Stan verfasserin; Gershenwald, Jeffrey E. verfasserin; Molldrem, Jeffrey J. verfasserin; Flamm, Anne L. verfasserin; Koivunen, Erkki verfasserin; Pentz, Rebecca D. verfasserin; Dias-Neto, Emmanuel verfasserin; Setubal, João C. verfasserin; Cahill, Dolores J. verfasserin; Troncoso, Patricia verfasserin; Do, Kim-Ahn verfasserin; Logothetis, Christopher J. verfasserin; Sidman, Richard L. verfasserin; Pasqualini, Renata verfasserin; Arap, Wadih verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 108, No. 46 (2011), p. 18637-18642
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Type of Publication: Article
Language: English
Published: 2011
Keywords: research-article
Online: Volltext
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