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IL-32, a Proinflammatory Cytokine in Rheumatoid Arthritis

IL-32 is a recently discovered cytokine that induces TNFα, IL-1β, IL-6, and chemokines. We investigated whether IL-32 is expressed in the synovia of patients with rheumatoid arthritis (RA) and studied associations with disease severity and the presence of other cytokines. Immunohistochemistry... Full description

1st Person: Joosten, Leo A. B.
Additional Persons: Netea, Mihai G. verfasserin; Kim, Soo-Hyun verfasserin; Yoon, Do-Young verfasserin; Oppers-Walgreen, Birgitte verfasserin; Radstake, Timothy R. D. verfasserin; Barrera, Pilar verfasserin; van de Loo, Fons A. J. verfasserin; Dinarello, Charles A. verfasserin; van den Berg, Wim B. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 103, No. 9 (2006), p. 3298-3303
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Type of Publication: Article
Language: English
Published: 2006
Keywords: research-article
autoimmune
inflammation
tumor necrosis factor
Online: Volltext
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