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Extracellular RNA Constitutes a Natural Procoagulant Cofactor in Blood Coagulation

Upon vascular injury, locally controlled haemostasis prevents life-threatening blood loss and ensures wound healing. Intracellular material derived from damaged cells at these sites will become exposed to blood components and could contribute to blood coagulation and pathological thrombus... Full description

1st Person: Kannemeier, Christian
Additional Persons: Shibamiya, Aya verfasserin; Nakazawa, Fumie verfasserin; Trusheim, Heidi verfasserin; Ruppert, Clemens verfasserin; Markart, Philipp verfasserin; Song, Yutong verfasserin; Tzima, Eleni verfasserin; Kennerknecht, Elisabeth verfasserin; Niepmann, Michael verfasserin; von Bruehl, Marie-Luise verfasserin; Sedding, Daniel verfasserin; Massberg, Steffen verfasserin; Günther, Andreas verfasserin; Engelmann, Bernd verfasserin; Preissner, Klaus T. verfasserin
Source: in Proceedings of the National Academy of Sciences of the United States of America Vol. 104, No. 15 (2007), p. 6388-6393
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Type of Publication: Article
Language: English
Published: 2007
Keywords: research-article
Contact phase activation
Thrombosis
RNase
Vascular injury
Wound healing
Online: Volltext
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