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Evaluation of Two Live, Cold-Passaged, Temperature-Sensitive Respiratory Syncytial Virus Vaccines in Chimpanzees and in Human Adults, Infants, and Children

Two live-attenuated, cold-passaged (cp), temperature-sensitive (ts) candidate vaccines, designated cpts530Z1009 and cpte248Z955, were attenuated, genetically stable, and immunogenic in chimpanzees and were highly attenuated for human adults. In respiratory syncytial virus (RSV)-seropositive... Full description

1st Person: Karron, Ruth A. verfasserin
Additional Persons: Wright, Peter F. verfasserin; Crowe, James E. verfasserin; Clements-Mann, Mary Lou verfasserin; Thompson, Juliette verfasserin; Makhene, Mamodikoe verfasserin; Casey, Roberta verfasserin; Murphy, Brian R. verfasserin
Source: in The Journal of Infectious Diseases Vol. 176, No. 6 (1997), p. 1428-1436
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Type of Publication: Article
Language: English
Published: 1997
Keywords: research-article
Online: Volltext
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