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Induction of Mucosal Immunity against Herpes Simplex Virus Type 1 in the Mouse Protects against Ocular Infection and Establishment of Latency

Immune responses were assessed after intranasal immunization of mice with a mixture of herpes simplex virus type 1 (HSV-1) glycoproteins with cholera toxin and its B subunit as adjuvant. Antigenspecific serum antibodies, which were largely IgG with IgGl the major subclass, neutralized virus in... Full description

1st Person: Richards, C. M. verfasserin
Additional Persons: Shimeld, C. verfasserin; Williams, N. A. verfasserin; Hill, T. J. verfasserin
Source: in The Journal of Infectious Diseases Vol. 177, No. 6 (1998), p. 1451-1457
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Type of Publication: Article
Language: English
Published: 1998
Keywords: research-article
Online: Volltext
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