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Safety and Immunogenicity of a New Tuberculosis Vaccine, MVA85A, in Healthy Adults in South Africa

Background. The efficacy of bacille Calmette-Guérin (BCG) may be enhanced by heterologous vaccination strategies that boost the BCG-primed immune response. One leading booster vaccine, MVA85A (where "MVA" denotes "modified vaccinia virus Ankara"), has shown promising safety and immunogenicity in... Full description

1st Person: Hawkridge, Tony verfasserin
Additional Persons: Scriba, Thomas J. verfasserin; Gelderbloem, Sebastian verfasserin; Smit, Erica verfasserin; Tameris, Michele verfasserin; Moyo, Sizulu verfasserin; Lang, Trudie verfasserin; Veldsman, Ashley verfasserin; Hatherill, Mark verfasserin; van der Merwe, Linda verfasserin; Fletcher, Helen A. verfasserin; Mahomed, Hassan verfasserin; Hill, Adrian V. S. verfasserin; Hanekom, Willem A. verfasserin; Hussey, Gregory D. verfasserin; McShane, Helen verfasserin
Source: in The Journal of Infectious Diseases Vol. 198, No. 4 (2008), p. 544-552
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Type of Publication: Article
Language: English
Published: 2008
Keywords: research-article
Online: Volltext
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