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Experimental Chemotherapy against Trypanosoma cruzi Infection: Essential Role of Endogenous Interferon-γ in Mediating Parasitologic Cure

Studies in humans and in experimental models suggest the involvement of the immune system for efficacy of drug treatment against protozoan parasites. This study tested this hypothesis by using various cytokine and inducible nitric oxide synthase (iNOS) knockout (KO) mice infected with Trypanosoma... Full description

1st Person: Romanha, Alvaro J.
Additional Persons: Alves, Rosana O. verfasserin; Murta, Silvane M. F. verfasserin; Silva, João S. verfasserin; Ropert, Catherine verfasserin; Gazzinelli, Ricardo T. verfasserin
Source: in The journal of infectious diseases : medical microbiology, clinical immunology, epidemiology Vol. 186, No. 6 (2002), p. 823-828
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Type of Publication: Article
Language: English
Published: 2002
Keywords: research-article
Online: Volltext
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