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DAS181, a Novel Sialidase Fusion Protein, Protects Mice from Lethal Avian Influenza H5N1 Virus Infection

Increasing resistance to currently available influenza antivirals highlights the need to develop alternate approaches for the prevention and/or treatment of influenza. DAS 181 (Fludase), a novel sialidase fusion protein that enzymatically removes sialic acids on respiratory epithelium, exhibits... Full description

1st Person: Belser, Jessica A. verfasserin
Additional Persons: Lu, Xiuhua verfasserin; Szretter, Kristy J. verfasserin; Jin, Xiaoping verfasserin; Aschenbrenner, Laura M. verfasserin; Lee, Alice verfasserin; Hawley, Stephen verfasserin; Kim, Do Hyong verfasserin; Malakhov, Michael P. verfasserin; Yu, Mang verfasserin; Fang, Fang verfasserin; Katz, Jacqueline M. verfasserin
Source: in The Journal of Infectious Diseases Vol. 196, No. 10 (2007), p. 1493-1499
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Type of Publication: Article
Language: English
Published: 2007
Keywords: research-article
Online: Volltext
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