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Hierarchy of Protein Assembly at the Vertex Ring Domain for Yeast Vacuole Docking and Fusion

Vacuole tethering, docking, and fusion proteins assemble into a "vertex ring" around the apposed membranes of tethered vacuoles before catalyzing fusion. Inhibitors of the fusion reaction selectively interrupt protein assembly into the vertex ring, establishing a causal assembly hierarchy: (a)... Full description

1st Person: Wang, Li
Additional Persons: Merz, Alexey J. verfasserin; Collins, Kevin M. verfasserin; Wickner, William verfasserin
Source: in The journal of cell biology : JCB Vol. 160, No. 3 (2003), p. 365-374
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Type of Publication: Article
Language: English
Published: 2003
Keywords: research-article
Membrane fusion
SNAREs
Yeast vacuoles
Rab GTPase
Actin
Online: Volltext
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