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Down-regulation of HSP60 expression by RNAi increases lipopolysaccharide- and cerulein-induced damages on isolated rat pancreatic tissues

The objective of this study was to investigate the function of heat shock protein 60 (HSP60) on pancreatic tissues by applying HSP60 small interfering RNA (siRNA) to reduce HSP60 expression. Rat pancreas was isolated and pancreatic tissue snips were prepared, cultured, and stimulated with low and... Full description

1st Person: Li, Yong-Yu
Additional Persons: Lu, Shuai verfasserin; Li, Kun verfasserin; Feng, Jia-Yan verfasserin; Li, Yan-Na verfasserin; Gao, Zhi-Rong verfasserin; Chen, Chang-Jie verfasserin
Source: in Cell stress & chaperones Vol. 15, No. 6 (2010), p. 965-975
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Type of Publication: Article
Language: English
Published: 2010
Keywords: research-article
Online: Volltext
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